Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 14/20 | 0.63 |
| ▸ | EDNRB | P24530 | 13/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010951 | 1.00 | EDNRA (0.63) | EDNRAEDNRBNPC1RAB9A | |
| SCHEMBL8080433 | 0.80 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL8622974 | 0.80 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL7665191 | 0.80 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL6951607 | 0.80 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL8621781 | 0.80 | EDNRA (0.68) | EDNRAEDNRB | |
| SCHEMBL7531517 | 0.79 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL8091942 | 0.78 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL8008619 | 0.78 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL7945618 | 0.78 | EDNRA (0.73) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143907-A | 3-phenyl-1-methylenedioxyphenyl-indane-2-carboxylic acid derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 2000-11-07 | — | — | US | disclosed |