⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13771846 | 0.76 | — | — | |
| SCHEMBL8328495 | 0.76 | — | — | |
| SCHEMBL22889658 | 0.74 | — | — | |
| SCHEMBL8237144 | 0.73 | — | — | |
| SCHEMBL12159439 | 0.73 | — | — | |
| SCHEMBL14705554 | 0.73 | — | — | |
| SCHEMBL14997122 | 0.71 | — | — | |
| SCHEMBL10073744 | 0.71 | — | — | |
| SCHEMBL13069965 | 0.69 | — | — | |
| SCHEMBL15521484 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543242-A1 | 8,9-DIHYDROIMIDAZOLE[1,2-A]PYRIMIDO[5,4-E]PYRIMIDINE-5(6H)-KETONE COMPOUND | Impact Therapeutics, Inc (CN) | 2019-09-25 | — | — | EP | disclosed |
| EP-2453018-B1 | A herbicide metabolizing protein, a gene thereof and use thereof | SUMITOMO CHEMICAL CO (JP) | 2016-03-16 | — | — | EP | disclosed |
| WO-2011146354-A1 | NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-11-24 | — | — | WO | disclosed |
| EP-1473333-B1 | INK-JET RECORDING INK AND METHOD OF INK-JET RECORDING | FUJIFILM CORP (JP) | 2010-09-22 | — | — | EP | disclosed |
| EP-2206547-A1 | Nitrogen-containing aromatic compounds and processes for the production of the same, polymers and proton conductive membranes of these compounds | JSR Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009143404-A1 | PIPERAZINE METABOTROPIC GLUTAMATE RECEPTOR 5 (MGLUR5) NEGATIVE ALLOSTERIC MODULATORS FOR ANXIETY/DEPRESSION | WYETH (US) | 2009-11-26 | — | — | WO | disclosed |
| EP-2116535-A1 | GLUCOKINASE-ACTIVATING SUBSTANCE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2009108657-A2 | HETEROARYL DERIVATIVES AS CFTR MODULATORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-09-03 | — | — | WO | disclosed |
| EP-1678166-B1 | PROTEIN KINASE INHIBITORS | UNIV ARIZONA (US) | 2009-07-29 | — | — | EP | disclosed |
| EP-2058321-A1 | Phosphorous containing monomer, polymer thereof, electrode for fuel cell including the polymer, electrolyte membrane for fuel cell including the polymer, and fuel cell using the electrode | Samsung Electronics Co., Ltd. (KR) | 2009-05-13 | — | — | EP | disclosed |
| EP-1667770-B1 | METHOD FOR THE PRODUCTION OF DERIVATIVES OF 4A,5,9,10,11,12-HEXAHYDROBENZOFURO [3A,3,2][ 2]- BENZAZEPINE | SANOCHEMIA PHARMAZEUTIKA AG (AT) | 2009-03-11 | — | — | EP | disclosed |
| WO-2009012277-A1 | METHOD FOR MODULATING GPR119 G PROTEIN-COUPLED RECEPTOR AND SELECTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-22 | — | — | WO | disclosed |
| EP-1608647-B1 | 5-PHENYLTHIAZOLE DERIVATIVES AND THEIR USE AS P13 KINASE INHIBITORS | NOVARTIS AG (CH) | 2008-01-09 | — | — | EP | disclosed |