Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 11/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025109 | 0.84 | MAPT (0.74) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL8015122 | 0.84 | MAPT (0.54) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL4254867 | 0.84 | MAPT (0.74) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL4254865 | 0.84 | MAPT (0.74) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL13801039 | 0.84 | MAPT (0.74) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL13780917 | 0.83 | MAPT (0.59) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL5420609 | 0.83 | MAPT (0.59) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL12793888 | 0.83 | MAPT (0.59) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL5420607 | 0.83 | MAPT (0.59) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL21697758 | 0.82 | MAPT (0.60) | MAPTALDH1A1MEN1TRPA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015877-A | ANTICARCINOGENIC AGENT WHICH INHIBITS ENDOPROTEASE ACTIVITY DIRECTED AGAINST SPECIFIC CYSTEINE CONTAINING CARBOXY TERMINAL MOTIF FOUND IN RAS PROTEINS AND OTHER SIGNAL TRANSDUCING G PROTEINS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-01-18 | — | — | US | disclosed |