Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 1.00 |
| ▸ | CA4 | P22748 | 4/20 | 0.67 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL72195 | 1.00 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL1332530 | 1.00 | — | — | |
| Acetic Acid SCHEMBL1331799 | 1.00 | — | — | |
| Acetic Acid SCHEMBL1332333 | 1.00 | — | — | |
| Acetic Acid SCHEMBL2289 | 1.00 | — | — | |
| Acetic Acid SCHEMBL2343612 | 1.00 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL10529780 | 1.00 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL1964006 | 1.00 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL153505 | 1.00 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL11467146 | 1.00 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096348-A | MIXTURE OF HYDROGEN PEROXIDE, DICARBOXYLIC ACID BUFFER AND WATER; MEDICAL EQUIPMENT | HEALTHPOINT, LTD. (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0881883-A1 | QUICK ACTING CHEMICAL STERILANT | Healthpoint, Ltd. (US) | 1998-12-09 | — | — | EP | disclosed |
| US-5827542-A | NONCORROSIVE TO METALS AND ELASTOMERS USED IN MEDICAL INSTRUMENTS; PEROXIDE, MALONIC ACID OR SALT | HEALTHPOINT, LTD. (US) | 1998-10-27 | — | — | US | disclosed |
| WO-1997028691-A1 | QUICK ACTING CHEMICAL STERILANT | HEALTHPOINT, LTD. (US) | 1997-08-14 | — | — | WO | disclosed |