Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77391 | 0.88 | PARP1 (0.75) | PARP1 | |
| SCHEMBL1824686 | 0.87 | PARP1 (0.86) | PARP1 | |
| SCHEMBL1689374 | 0.87 | PARP1 (0.81) | PARP1 | |
| SCHEMBL87093 | 0.86 | PARP1 (0.74) | PARP1 | |
| SCHEMBL27015353 | 0.86 | PARP1 (0.80) | PARP1 | |
| SCHEMBL77530 | 0.85 | PARP1 (0.75) | PARP1 | |
| SCHEMBL19569946 | 0.85 | PARP1 (0.93) | PARP1 | |
| SCHEMBL30415984 | 0.84 | PARP1 (1.00) | PARP1 | |
| SCHEMBL1689488 | 0.84 | PARP1 (1.00) | PARP1 | |
| SCHEMBL79291 | 0.83 | PARP1 (0.78) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093032-A1 | PHTHALAZINONE DERIVATIVES | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | WO | disclosed |