SCHEMBL8013602

SCHEMBL8013602

CC(=O)CC(=O)N1CCNCC1C

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.44
PLD1 Q13393 1/20 0.35
KHK P50053 1/20 0.34
ENPP2 Q13822 1/20 0.32
FAP Q12884 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
PAK4 O96013 4/20 0.31
SMYD3 Q9H7B4 6/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
HPGD P15428 1/20 0.31
DPP7 Q9UHL4 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM3 P20309 1/20 0.30
PAK1 Q13153 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13885747 0.82 DPP4 (0.46) DPP4PLD1KHKENPP2FAP
SCHEMBL618524 0.82 DPP4 (0.46) DPP4PLD1KHKENPP2SMYD3
SCHEMBL617648 0.82 DPP4 (0.46) DPP4PLD1KHKENPP2SMYD3
SCHEMBL7570761 0.82 DPP4 (0.46) DPP4PLD1KHKENPP2SMYD3
SCHEMBL7375420 0.81 DPP4 (0.43) DPP4PLD1KHKENPP2FAP
SCHEMBL3714781 0.81 DPP4 (0.45) DPP4PLD1KHKENPP2SMN1; SMN2
Hydrochloric Acid SCHEMBL17560352 0.81 DPP4 (0.45) DPP4PLD1KHKENPP2SMYD3
SCHEMBL27980532 0.80 DPP4 (0.30) DPP4FAPDPP8DPP9
SCHEMBL747476 0.80 DPP4 (0.40) DPP4PLD1KHKENPP2PAK4
SCHEMBL2321580 0.80 DPP4 (0.40) DPP4PLD1KHKENPP2PAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970137-A1 COATING, ADHESIVE AND SEALANT COMPOSITIONS International Coatings Limited (GB) 2000-01-12 EP disclosed
WO-1998041561-A1 COATING, ADHESIVE AND SEALANT COMPOSITIONS INTERNATIONAL COATINGS LIMITED (GB) 1998-09-24 WO disclosed