Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.45 |
| ▸ | APAF1 | O14727 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.45 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362944 | 0.91 | TDP1 (0.48) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL8557032 | 0.91 | TDP1 (0.45) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL8017838 | 0.90 | NR1I2 (0.51) | TDP1APEX1LMNATSHRL3MBTL1 | |
| SCHEMBL8017831 | 0.90 | NR1I2 (0.51) | TDP1APEX1LMNATSHRL3MBTL1 | |
| SCHEMBL8012721 | 0.88 | NR1I2 (0.51) | TDP1APEX1LMNATSHRL3MBTL1 | |
| SCHEMBL8013445 | 0.88 | NR1I2 (0.43) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL8013449 | 0.88 | NR1I2 (0.43) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL10993022 | 0.86 | NR1I2 (0.51) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL10993033 | 0.86 | NR1I2 (0.51) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL9413830 | 0.86 | NR1I2 (0.51) | TDP1APAF1APEX1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077952-A | Cephaloporins and homologues | PFIZER INC. (US) | 2000-06-20 | — | — | US | disclosed |
| US-6020329-A | Cephaloporins and homologues, preparations and pharmaceutical compositions | PZIFER INC. (US) | 2000-02-01 | — | — | US | disclosed |
| WO-1992001696-A1 | CEPHALOSPORINS AND HOMOLOGUES, PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1992-02-06 | — | — | WO | disclosed |