Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571 | 0.80 | MAPT (0.67) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL25049822 | 0.80 | MAPT (0.67) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL27514359 | 0.78 | MAPT (0.64) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL6968554 | 0.78 | MAPT (0.64) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL27888039 | 0.78 | MAPT (0.64) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| Methyl Alcohol SCHEMBL5282426 | 0.78 | MAPT (0.64) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| Hydrogen Peroxide SCHEMBL1652477 | 0.78 | MAPT (0.64) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| Hydrochloric Acid SCHEMBL8899483 | 0.78 | MAPT (0.64) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL29033303 | 0.78 | MAPT (0.64) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL343807 | 0.78 | MAPT (0.64) | MAPTKMT2ACYP2C19HIF1AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073713-A1 | OXIMYL MACROCYCLIC DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
| US-20080146808-A1 | AZABICYCLO-OCTANE INHIBITORS OF IAP | GENENTECH, INC. (US) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146808-A1 | AZABICYCLO-OCTANE INHIBITORS OF IAP | XIAP, BIRC3, BIRC2 | MAPT 4738/4885KMT2A 3778/4885CYP2C19 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.