SCHEMBL8014286

SCHEMBL8014286

CCCCCCCC/C=C\CCCCCCCCOCC(CNC(=O)CCCN(CC)CC)OCCCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 12/20 0.61
LPAR1 Q92633 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8004843 0.92 TLR2 (0.59) TLR2LPAR1
SCHEMBL8015753 0.90 TLR2 (0.63) TLR2LPAR1
SCHEMBL8016936 0.85 TLR2 (0.50) TLR2
SCHEMBL8016932 0.85 TLR2 (0.50) TLR2
SCHEMBL8013672 0.83 TLR2 (0.48) TLR2LPAR1
SCHEMBL8016729 0.83 CNR1 (0.53) LPAR1
SCHEMBL8016728 0.83 CNR1 (0.53) LPAR1
SCHEMBL2835420 0.82 CNR1 (0.51)
SCHEMBL8021323 0.81 TLR2 (0.46) TLR2
SCHEMBL8013682 0.81 TLR2 (0.45) TLR2LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0685234-B1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU CO LTD (JP) 2000-05-10 EP disclosed
US-6020317-A Glycerol derivative, device and pharmaceutical composition NIPPON SHINYAKU CO. LTD. (JP) 2000-02-01 US disclosed
EP-0685457-A1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed
EP-0685234-A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed