Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1933912 | 0.92 | MEN1 (0.49) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL21657581 | 0.91 | MEN1 (0.48) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL29172381 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4CALDH1A1TBXA2R | |
| SCHEMBL6526800 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4CALDH1A1TBXA2R | |
| SCHEMBL10518204 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4CALDH1A1TBXA2R | |
| SCHEMBL29148468 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4CALDH1A1TBXA2R | |
| SCHEMBL5118077 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4CALDH1A1TBXA2R | |
| SCHEMBL4100095 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4CALDH1A1TBXA2R | |
| SCHEMBL11577255 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4CALDH1A1TBXA2R | |
| SCHEMBL1532127 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4CALDH1A1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063416-A2 | F18-LABELED OXA FATTY ACIDS AND METHODS OF MAKING AND USING THE SAME | DUKE UNIVERSITY (US) | 2000-10-26 | — | — | WO | disclosed |