SCHEMBL8014473

SCHEMBL8014473

CCCC[C@H]1CC[C@H](CO[C@H]2CC[C@H](C(=O)Oc3cc(F)c(F)c(F)c3)CC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
GAA P10253 1/20 0.39
NAAA Q02083 1/20 0.34
POLB P06746 2/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.34
GPR119 Q8TDV5 2/20 0.33
CA2 P00918 1/20 0.33
TP53 P04637 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
SCN9A Q15858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8014698 0.97 MAPT (0.37) MAPTGAANAAAPOLBHPGD
SCHEMBL8014695 0.97 MAPT (0.37) MAPTGAANAAAPOLBHPGD
SCHEMBL8018347 0.97 MAPT (0.37) MAPTGAANAAAPOLBHPGD
SCHEMBL8014704 0.97 MAPT (0.37) MAPTGAANAAAPOLBHPGD
SCHEMBL8017367 0.97 GAA (0.36) MAPTGAANAAAKMT2AGPR119
SCHEMBL8021281 0.96 MEN1 (0.36) MAPTGAANAAAKMT2AGPR119
SCHEMBL8013908 0.96 MEN1 (0.36) MAPTGAANAAAKMT2AGPR119
SCHEMBL8014666 0.96 MEN1 (0.36) MAPTGAANAAAKMT2AGPR119
SCHEMBL8014357 0.96 MEN1 (0.36) MAPTGAANAAAKMT2AGPR119
SCHEMBL8016987 0.96 MEN1 (0.36) MAPTGAANAAAKMT2AGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6149990-A Carboxylate derivatives comprising an ether group and liquid crystal composition comprising the same CHISSO CORPORATION (JP) 2000-11-21 US disclosed
EP-0884302-A1 CARBOXYLIC ESTER DERIVATIVES CONTAINING ETHER GROUP AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME CHISSO CORPORATION (JP) 1998-12-16 EP disclosed