Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 3/20 | 0.37 |
| ▸ | GABRD | O14764 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.37 |
| ▸ | GABRE | P78334 | 3/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420751 | 1.00 | GSR (0.48) | GSRGABRR1SLC7A5CPB2RNPEP | |
| SCHEMBL2420748 | 1.00 | GSR (0.48) | GSRGABRR1SLC7A5CPB2RNPEP | |
| SCHEMBL5319928 | 0.94 | GSR (0.57) | GSRGABRR1SLC7A5CPB2RNPEP | |
| SCHEMBL5323156 | 0.92 | GSR (0.55) | GSRGABRR1SLC7A5CPB2RNPEP | |
| SCHEMBL2330401 | 0.86 | GABRR1 (0.56) | GSRGABRR1SLC7A5RNPEPGABRP | |
| SCHEMBL2424605 | 0.86 | GABRR1 (0.56) | GSRGABRR1SLC7A5RNPEPGABRP | |
| SCHEMBL8018052 | 0.86 | GABRR1 (0.56) | GSRGABRR1SLC7A5RNPEPGABRP | |
| SCHEMBL3515974 | 0.86 | GABRR1 (0.56) | GSRGABRR1SLC7A5RNPEPGABRP | |
| SCHEMBL2324416 | 0.86 | GABRR1 (0.56) | GSRGABRR1SLC7A5RNPEPGABRP | |
| SCHEMBL2334387 | 0.86 | GABRR1 (0.56) | GSRGABRR1SLC7A5RNPEPGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127420-A | SELECTIVE, IRREVERSIBLE INHIBITORS OF NEURONAL ISOFORM OF NITRIC OXIDE SYNTHASE PRODUCING NITRIC OXIDE; MIGRAINE HEADACHES, STROKE, PAIN INCLUDING CHRONIC VISCERAL PAIN, DRUG ADDICTION, PARKINSON'S DISEASE, SCHIZOPHRENIA, ANTIEPILEPTIC | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 2000-10-03 | — | — | US | disclosed |