⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14372424 | 0.97 | — | — | |
| SCHEMBL19713079 | 0.90 | — | — | |
| SCHEMBL19713075 | 0.88 | — | — | |
| SCHEMBL1230461 | 0.79 | — | — | |
| SCHEMBL14456212 | 0.69 | — | — | |
| SCHEMBL13531216 | 0.67 | — | — | |
| SCHEMBL15395269 | 0.66 | — | — | |
| SCHEMBL13160604 | 0.66 | — | — | |
| SCHEMBL15114471 | 0.64 | — | — | |
| SCHEMBL7598 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245009-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 5-BIPHENYL-4-YL-2-METHYLPENTANOIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2016-08-10 | — | — | EP | disclosed |
| US-9403766-B2 | Intermediates for producing NEP inhibitors or prodrugs thereof | NOVARTIS AG (CH) | 2016-08-02 | — | — | US | disclosed |
| US-20160060217-A1 | Processes | HOOK DAVID (CH) | 2016-03-03 | — | — | US | disclosed |
| US-9227934-B2 | Processes for producing NEP inhibitors or prodrugs thereof | NOVARTIS AG (CH) | 2016-01-05 | — | — | US | disclosed |
| US-20150246881-A1 | Processes | NOVARTIS AG (CH) | 2015-09-03 | — | — | US | disclosed |
| US-9061973-B2 | Processes for producing NEP inhibitors or prodrugs thereof | NOVARTIS PHARMACEUTICALS CORPORATION (US) | 2015-06-23 | — | — | US | disclosed |
| US-20140243546-A1 | Processes | NOVARTIS AG (CH) | 2014-08-28 | — | — | US | disclosed |
| US-8580974-B2 | Processes | NOVARTIS AG (CH) | 2013-11-12 | — | — | US | disclosed |
| US-8580974-B2 | Processes | NOVARTIS AG (CH) | 2013-11-12 | — | — | US | disclosed |
| US-20110046397-A1 | NEW PROCESSES | NOVARTIS PHARMACEUTICALS CORPORATION | 2011-02-24 | — | — | US | disclosed |
| US-20110046397-A1 | NEW PROCESSES | NOVARTIS PHARMACEUTICALS CORPORATION | 2011-02-24 | — | — | US | disclosed |
| WO-2009090251-A2 | NEW PROCESSES | NOVARTIS AG (CH) | 2009-07-23 | — | — | WO | disclosed |
| WO-2007058979-A1 | PROCESS FOR THE PRODUCTION OF MERCAPTOALKYLALKOXYSILANES | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2007-05-24 | — | — | WO | disclosed |