Stearyl Fumaric Acid

Stearyl Fumaric Acid

SCHEMBL8015803

C=COC(C)=O.CCCCCCCCCCCCCCCCCCOC(=O)C=CC(=O)O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.74
ATM Q13315 1/20 0.53
TSHR P16473 4/20 0.46
HPGD P15428 1/20 0.46
MAPT P10636 2/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 1/20 0.42
APP P05067 3/20 0.41
PRKCA P17252 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
NAAA Q02083 1/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HTT P42858 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Stearyl Fumaric Acid SCHEMBL8015800 1.00 HCAR2 (0.74) HCAR2ATMTSHRHPGDMAPT
SCHEMBL7994827 1.00 HCAR2 (0.74) HCAR2ATMTSHRHPGDMAPT
SCHEMBL8602279 1.00 HCAR2 (0.74) HCAR2ATMTSHRHPGDMAPT
SCHEMBL7994831 1.00 HCAR2 (0.74) HCAR2ATMTSHRHPGDMAPT
SCHEMBL8602281 1.00 HCAR2 (0.74) HCAR2ATMTSHRHPGDMAPT
Butyl Fumarate SCHEMBL9462953 0.94 HCAR2 (0.73) HCAR2ATMTSHRHPGDMAPT
Butyl Fumarate SCHEMBL9679785 0.94 HCAR2 (0.73) HCAR2ATMTSHRHPGDMAPT
SCHEMBL9508429 0.94 HCAR2 (0.63) HCAR2ATMTSHRHPGDMAPT
SCHEMBL8601584 0.94 HCAR2 (0.63) HCAR2ATMTSHRHPGDMAPT
SCHEMBL8526243 0.94 HCAR2 (0.63) HCAR2ATMTSHRHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0807130-B1 WATERBORNE (METH)ACRYLIC LATEX POLYMERS FOR RELEASE MINNESOTA MINING & MFG (US) 2000-02-16 EP disclosed
EP-0807130-A1 WATERBORNE (METH)ACRYLIC LATEX POLYMERS FOR RELEASE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-19 EP disclosed
EP-0448399-B1 Waterborne acrylic low adhesion backsize and release coating compositions, methods of making the compositions, and sheet materials coated therewith MINNESOTA MINING & MFG (US) 1996-08-21 EP disclosed
WO-1996023820-A1 WATERBORNE (METH)ACRYLIC LATEX POLYMERS FOR RELEASE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-08 WO disclosed
US-5516865-A EMULSION COPOLYMERIZATION PRODUCT OF LONG AND SHORT CHAIN ALKYL (METH)ACRYLATE COMONOMERS; SOLVENT-FREE; RELEASE COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-14 US disclosed
US-5350631-A Water-borne low adhesion backsize and release coating compositions, methods of making the compositions, and sheet materials coated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-09-27 US disclosed
US-5225480-A Latex release coatings formed by emulsion polymerization in the presence of a free radical catalyst MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-07-06 US disclosed
EP-0448399-A2 Waterborne acrylic low adhesion backsize and release coating compositions, methods of making the compositions, and sheet materials coated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-25 EP disclosed