Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619931 | 0.89 | TSHR (0.35) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL7621397 | 0.86 | TSHR (0.35) | TSHRHPGDALDH1A1TP53CYP3A4 | |
| SCHEMBL7619879 | 0.85 | TSHR (0.35) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL6872530 | 0.84 | TSHR (0.34) | TSHRHPGDALDH1A1TP53CYP3A4 | |
| SCHEMBL4641787 | 0.79 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL11490781 | 0.77 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL11054551 | 0.75 | KLK7 (0.50) | ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL27995174 | 0.73 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL8648130 | 0.73 | TSHR (0.42) | TSHRHPGDTHRBHDAC7HDAC8 | |
| SCHEMBL11590481 | 0.72 | TSHR (0.39) | TSHRHPGDTHRBHDAC7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000001664-A1 | RADIATION-CURABLE COMPOUND | DSM N.V. (NL) | 2000-01-13 | — | — | WO | disclosed |
| EP-0970945-A1 | Radiation curable acrylic-acid esters containing hydroxyalkylamide groups | DSM N.V. (NL) | 2000-01-12 | — | — | EP | disclosed |