SCHEMBL80163

SCHEMBL80163

OCc1cccc(OCc2ccccc2)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.74
CYP4A11 Q02928 1/20 0.74
TSHR P16473 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
BCHE P06276 3/20 0.64
MAOB P27338 5/20 0.62
NR4A2 P43354 1/20 0.62
GPBAR1 Q8TDU6 1/20 0.59
CYSLTR1 Q9Y271 1/20 0.59
KDM4E B2RXH2 1/20 0.58
MEN1 O00255 1/20 0.58
ALDH1A1 P00352 1/20 0.58
GAA P10253 1/20 0.58
MAPT P10636 1/20 0.58
THRB P10828 1/20 0.58
PKM P14618 1/20 0.58
RAB9A P51151 1/20 0.58
BLM P54132 1/20 0.58
KMT2A Q03164 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29462055 1.00 CYP4F2 (0.74) CYP4F2CYP4A11TSHRSMN1; SMN2BCHE
SCHEMBL27736763 0.89 SMN1; SMN2 (0.65) CYP4F2CYP4A11TSHRSMN1; SMN2BCHE
SCHEMBL28893553 0.89 TSHR (0.59) CYP4F2CYP4A11TSHRSMN1; SMN2MAOB
SCHEMBL29961933 0.89 TSHR (0.59) CYP4F2CYP4A11TSHRSMN1; SMN2MAOB
SCHEMBL3271153 0.86 CYP4F2 (0.61) CYP4F2CYP4A11TSHRSMN1; SMN2BCHE
SCHEMBL4910012 0.86 MEN1 (0.62) CYP4F2CYP4A11TSHRSMN1; SMN2BCHE
SCHEMBL11121827 0.86 SMN1; SMN2 (0.66) CYP4F2CYP4A11TSHRSMN1; SMN2MAOB
SCHEMBL15761340 0.86 BCHE (0.70) CYP4F2CYP4A11SMN1; SMN2BCHEMAOB
SCHEMBL1268719 0.86 MAOB (0.81) CYP4F2CYP4A11BCHEMAOBNR4A2
SCHEMBL3179250 0.85 CYP4F2 (1.00) CYP4F2CYP4A11TSHRSMN1; SMN2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
EP-1575495-A2 COMPOUNDS AND METHODS SmithKline Beecham Corporation (US) 2005-09-21 EP claimed
WO-2003082205-A2 COMPOUNDS AND METHODS SMITHKLINE BEECHAM CORPORATION (US) 2003-10-09 WO claimed
US-6319310-B1 FOR ACOUSTIC INK JET PRINTING; TRANSPARENCY, GLOSS, CREASE RESISTANCE XEROX CORPORATION 2001-11-20 US claimed
EP-0674232-B1 Recording sheets XEROX CORP (US) 2000-05-31 EP claimed
US-5922117-A Ink compositions containing alcohols XEROX CORPORATION (US) 1999-07-13 US claimed
US-5663022-A Recording sheets XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0674232-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0526537-A1 5-BENZYL BARBITURATE DERIVATIVES. UNIV BROWN RES FOUND (US) 1993-02-10 EP claimed
WO-1991016315-A1 5-BENZYL BARBITURATE DERIVATIVES BROWN UNIVERSITY RESEARCH FOUNDATION (US) 1991-10-31 WO claimed
EP-4663636-A2 TRIFLUOROMETHYL SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS BioCryst Pharmaceuticals, Inc. (US) 2025-12-17 EP disclosed
US-20250270171-A1 HUMAN PLASMA KALLIKREIN INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2025-08-28 US disclosed
EP-4578856-A1 HETEROCYCLIC COMPOUND Ubience Inc. (JP) 2025-07-02 EP disclosed
EP-4180424-B1 SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS BIOCRYST PHARM INC (US) 2025-06-25 EP disclosed
US-4241081-A Cyclopropanecarboxylate pesticides SHELL OIL COMPANY (US) 1980-12-23 US disclosed
US-4237123-A INSECTICIDES, MITICIDES SHELL OIL COMPANY (US) 1980-12-02 US disclosed
US-4225612-A Heterocyclic-substituted cyclopropanecarboxylate pesticides SHELL OIL COMPANY (US) 1980-09-30 US disclosed
US-4211792-A Oxyimino-substituted (1R,trans)-cyclopropanecarboxylate pesticides SHELL OIL COMPANY (US) 1980-07-08 US disclosed
EP-0005882-A1 A method of combating acarine pests by means of oxyimino-substituted cyclopropane-carboxylate esters, Z-isomers of certain such esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-12-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270171-A1 HUMAN PLASMA KALLIKREIN INHIBITORS KLKB1, KLK5, KLK1 CYP4F2 991/4885CYP4A11 690/4885TSHR 3844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.