SCHEMBL8016997

SCHEMBL8016997

CC(C)CN(C[C@H](O)C(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MME P08473 14/20 0.75
ACE P12821 9/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8016991 1.00 MME (0.75) MMEACE
SCHEMBL8016944 0.94 MME (0.85) MMEACE
SCHEMBL8016940 0.94 MME (0.85) MMEACE
SCHEMBL8033010 0.94 MME (0.66) MMEACE
SCHEMBL8033016 0.94 MME (0.66) MMEACE
SCHEMBL8027170 0.91 MME (0.88) MMEACE
SCHEMBL8032885 0.91 MME (0.88) MMEACE
SCHEMBL8032876 0.91 MME (0.88) MMEACE
SCHEMBL8029480 0.91 MME (0.75) MMEACE
SCHEMBL8029476 0.91 MME (0.75) MMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0738711-B1 NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP SANTEN PHARMACEUTICAL CO LTD (JP) 2000-03-08 EP disclosed
EP-0738711-A1 NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP SANTEN PHARMACEUTICAL CO., LTD. (JP) 1996-10-23 EP disclosed