Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012876 | 1.00 | MEN1 (0.51) | MEN1KMT2AGAATDP1CYP1A2 | |
| SCHEMBL21001852 | 0.91 | MEN1 (0.60) | MEN1KMT2AGAATDP1CYP1A2 | |
| SCHEMBL1262487 | 0.87 | MEN1 (0.54) | MEN1KMT2AGAATDP1HTT | |
| SCHEMBL8026936 | 0.87 | MEN1 (0.54) | MEN1KMT2AGAATDP1HTT | |
| SCHEMBL18760388 | 0.85 | MEN1 (0.53) | MEN1KMT2AGAATDP1CYP1A2 | |
| SCHEMBL6224692 | 0.83 | CYP1A2 (0.44) | MEN1KMT2AGAATDP1CYP1A2 | |
| SCHEMBL8465153 | 0.83 | CYP1A2 (0.44) | MEN1KMT2AGAATDP1CYP1A2 | |
| SCHEMBL28220300 | 0.83 | CYP1A2 (0.44) | MEN1KMT2AGAATDP1CYP1A2 | |
| SCHEMBL26790537 | 0.83 | MEN1 (0.54) | MEN1KMT2AGAATDP1CYP1A2 | |
| SCHEMBL15723436 | 0.81 | MEN1 (0.65) | MEN1KMT2AGAATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245009-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 5-BIPHENYL-4-YL-2-METHYLPENTANOIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2016-08-10 | — | — | EP | disclosed |
| WO-2009090251-A2 | NEW PROCESSES | NOVARTIS AG (CH) | 2009-07-23 | — | — | WO | disclosed |