Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 15/20 | 0.76 |
| ▸ | ACE | P12821 | 11/20 | 0.76 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017181 | 1.00 | MME (0.76) | MMEACEGPR34CPA1ACE2 | |
| SCHEMBL8017006 | 0.97 | MME (0.80) | MMEACEGPR34CPA1ACE2 | |
| SCHEMBL8028946 | 0.97 | MME (0.80) | MMEACEGPR34CPA1ACE2 | |
| SCHEMBL8032897 | 0.97 | MME (0.80) | MMEACEGPR34CPA1ACE2 | |
| SCHEMBL8032600 | 0.97 | MME (0.80) | MMEACEGPR34CPA1ACE2 | |
| SCHEMBL8017013 | 0.97 | MME (0.80) | MMEACEGPR34CPA1ACE2 | |
| SCHEMBL27442633 | 0.95 | MME (0.67) | MMEACE | |
| SCHEMBL8027307 | 0.93 | MME (0.74) | MMEACEGPR34CPA1ACE2 | |
| SCHEMBL8027313 | 0.93 | MME (0.74) | MMEACEGPR34CPA1ACE2 | |
| SCHEMBL8027319 | 0.93 | MME (0.72) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |