Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013574 | 0.85 | TACR1 (0.46) | MEN1LMNAHTR1EHTTKMT2A | |
| SCHEMBL9002757 | 0.82 | TACR1 (0.44) | TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL8017603 | 0.80 | TACR1 (0.54) | TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL25122261 | 0.80 | CYP2C9 (0.47) | MEN1HTTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL25122224 | 0.80 | CYP2C9 (0.47) | MEN1HTTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL25122248 | 0.80 | CYP2C9 (0.47) | MEN1HTTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL25122378 | 0.80 | CYP2C9 (0.47) | MEN1HTTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL25122278 | 0.80 | CYP2C9 (0.47) | MEN1HTTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL23007438 | 0.80 | CYP2C9 (0.47) | MEN1HTTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL9002892 | 0.79 | CMA1 (0.50) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000034804-A1 | HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-06-15 | — | — | WO | claimed |