Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.74 |
| ▸ | ACE | P12821 | 11/20 | 0.74 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 6/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.48 |
| ▸ | CPA1 | P15085 | 3/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017298 | 1.00 | MME (0.74) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL27504886 | 1.00 | MME (0.74) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL9007758 | 0.95 | MME (0.66) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL9007760 | 0.95 | MME (0.66) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL8028927 | 0.95 | MME (0.66) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL8028923 | 0.95 | MME (0.66) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL8452763 | 0.93 | MME (0.73) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL8027670 | 0.93 | MME (0.73) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL8027674 | 0.93 | MME (0.73) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL8016959 | 0.93 | MME (0.66) | MMEACEITGA4ITGB7ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |