Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 14/20 | 0.79 |
| ▸ | ACE | P12821 | 12/20 | 0.79 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032604 | 0.91 | MME (0.77) | MMEACE | |
| SCHEMBL8032597 | 0.91 | MME (0.77) | MMEACE | |
| SCHEMBL8029619 | 0.90 | MME (0.70) | MMEACEPTPN1PIN1 | |
| SCHEMBL8032883 | 0.89 | MME (0.71) | MMEACE | |
| SCHEMBL8032875 | 0.89 | MME (0.71) | MMEACE | |
| SCHEMBL8027151 | 0.89 | MME (1.00) | MMEACEPIN1 | |
| SCHEMBL8032890 | 0.89 | MME (1.00) | MMEACEPIN1 | |
| SCHEMBL6440665 | 0.89 | MME (1.00) | MMEACEPIN1 | |
| SCHEMBL8030485 | 0.89 | MME (1.00) | MMEACEPIN1 | |
| SCHEMBL8033744 | 0.89 | MME (1.00) | MMEACEPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |