SCHEMBL8017664

SCHEMBL8017664

CC1=C(C)C(C)(C)C([Hf]C2(C)C(c3ccccc3)=Cc3ccccc32)=C1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6285542 0.99 ESR1 (0.33) ESR1ESR2
Hydrochloric Acid SCHEMBL6289889 0.75 ESR1 (0.40) ESR1ESR2
SCHEMBL7030526 0.71 ESR1 (0.34) ESR1ESR2
Hydrochloric Acid SCHEMBL6287022 0.70 ESR1 (0.33) ESR1ESR2
Hydrochloric Acid SCHEMBL6287015 0.70 ESR1 (0.33) ESR1ESR2
Hydrochloric Acid SCHEMBL6285342 0.69 ESR1 (0.38) ESR1ESR2
Hydrochloric Acid SCHEMBL6285534 0.69 ESR1 (0.33) ESR1ESR2
SCHEMBL6285741 0.69 ESR1 (0.33) ESR1ESR2
SCHEMBL23203536 0.69
Hydrochloric Acid SCHEMBL23203531 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1062257-A1 ETHYLENE COPOLYMERS WITH NARROW COMPOSITION DISTRIBUTION AND HIGH MELTING TEMPERATURES, AND METHODS OF PRODUCTION THEREOF THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2000-12-27 EP disclosed
WO-2000040625-A1 ETHYLENE COPOLYMERS WITH NARROW COMPOSITION DISTRIBUTION AND HIGH MELTING TEMPERATURES, AND METHODS OF PRODUCTION THEREOF THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2000-07-13 WO disclosed