SCHEMBL8018

SCHEMBL8018

CC(C)(C)OC(=O)N1CCC(N)CC1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.58
RECQL P46063 1/20 0.55
EPHX1 P07099 1/20 0.55
USP2 O75604 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MAPT P10636 2/20 0.54
KDM4E B2RXH2 1/20 0.54
THRB P10828 1/20 0.54
GPR119 Q8TDV5 6/20 0.51
PTPN2 P17706 1/20 0.50
PTPN1 P18031 1/20 0.50
PTPN6 P29350 1/20 0.50
ALDH1A1 P00352 2/20 0.48
NPC1 O15118 1/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
RAB9A P51151 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL307023 0.98 HPGD (0.57) HPGDRECQLEPHX1USP2SMN1; SMN2
Acetic Acid SCHEMBL6198968 0.95 HPGD (0.54) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL4171034 0.93 HPGD (0.60) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL4171032 0.93 HPGD (0.60) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL28357552 0.93 HPGD (0.53) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL328895 0.93 HPGD (0.60) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL4177716 0.92 HPGD (0.63) HPGDRECQLEPHX1USP2SMN1; SMN2
Sulfuric Acid SCHEMBL7983173 0.92 HPGD (0.51) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL23077692 0.90 HPGD (0.50) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL4161964 0.90 HPGD (0.50) HPGDRECQLEPHX1USP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8786 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036730-A Gαq/11 protein inhibitor with purine skeleton, and preparation method and application thereof 中山大学 2026-05-15 CN claimed
CN-122010902-A Carbonyl substituted pyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof 山东大学 2026-05-12 CN claimed
CN-119528880-A HIV-1 non-nucleoside reverse transcriptase inhibitor and preparation method and application thereof 复旦大学 2025-02-28 CN claimed
CN-118994150-A Preparation method of intermediate of riliebatan 中山奕安泰医药科技有限公司 2024-11-22 CN claimed
CN-118146226-A Pyrrolo [2,3-d ] pyrimidine compound with nitrogen-containing heterocyclic structure, and preparation method and application thereof 贵州大学 2024-06-07 CN claimed
CN-113881509-B Pore-forming agent and preparation method thereof 深圳市励高表面处理材料有限公司 2024-06-07 CN claimed
CN-115160300-B Coumarin compound, preparation method thereof and application of coumarin compound in resisting Alzheimer disease 中国人民解放军北部战区总医院 2024-05-31 CN claimed
CN-117430616-A Pyrimido ring compound containing deuterated methyl, preparation method and application thereof 复旦大学 2024-01-23 CN claimed
CN-117247347-A Preparation method of N-Boc-4-aminopiperidine 安徽昊帆生物有限公司 2023-12-19 CN claimed
CN-116947879-A BBI608 derivative, preparation method thereof and application thereof in preparing medicines for treating STAT3 mediated diseases 沈阳药科大学 2023-10-27 CN claimed
CN-101479261-A 3-pyrazolyl-benzamide-4-ethers, secondary amines thereof and derivatives thereof as modulators of the serotonin receptor 5-HT 2A for the treatment of disorders related thereto ARENA PHARM INC (US) 2009-07-08 CN claimed
EP-2027119-A2 ETHERS, SECONDARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO Arena Pharmaceuticals, Inc. (US) 2009-02-25 EP claimed
EP-1490367-B1 IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS GLAXO GROUP LTD (GB) 2008-07-23 EP claimed
US-7348339-B2 2-(4-amino-furazan-3-yl)-1-ethyl-N-[(2R)-2-morpholinylmethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide; Mitogen- and Stress-Activated Protein (MSK) and Rho (guanosine triphosphate) 1 or 2 kinase inhibitor; neurodegenerative diaeases; antiinflammatory, anticarcinogenic, antiviral and antibacterial agent GLAXO GROUP LIMITED (GB) 2008-03-25 US claimed
WO-2007136680-A2 3-PYRAZ0LYL-BENZAMIDE-4-ETHERS, SECONDARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2007-11-29 WO claimed
WO-2006137658-A1 NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DONGBU HITEK CO., LTD. (KR) 2006-12-28 WO claimed
EP-1121372-B1 ADENINE DERIVATIVES PFIZER LTD (GB) 2006-06-28 EP claimed
US-6326359-B1 PURINE DERIVATIVES PFIZER INC 2001-12-04 US claimed
EP-1121372-A1 ADENINE DERIVATIVES Pfizer Limited (GB) 2001-08-08 EP claimed
WO-2000023457-A1 ADENINE DERIVATIVES PFIZER LIMITED (GB) 2000-04-27 WO claimed