Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2619847 | 1.00 | KMT2A (0.35) | KMT2ADPP8DPP9EPHX2CASP3 | |
| SCHEMBL2619850 | 1.00 | KMT2A (0.35) | KMT2ADPP8DPP9EPHX2CASP3 | |
| SCHEMBL8028572 | 1.00 | KMT2A (0.35) | KMT2ADPP8DPP9EPHX2CASP3 | |
| SCHEMBL2926269 | 1.00 | KMT2A (0.35) | KMT2ADPP8DPP9EPHX2CASP3 | |
| SCHEMBL4359876 | 0.83 | EPHX1 (0.34) | — | |
| SCHEMBL2619825 | 0.81 | KMT2A (0.36) | KMT2ADPP8DPP9EPHX2CASP3 | |
| SCHEMBL7918847 | 0.81 | KMT2A (0.36) | KMT2ADPP8DPP9EPHX2CASP3 | |
| SCHEMBL2108782 | 0.80 | — | — | |
| SCHEMBL2108751 | 0.80 | — | — | |
| SCHEMBL2108748 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091016-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-23 | — | — | WO | disclosed |