Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028524 | 0.89 | GAA (0.41) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL7933847 | 0.87 | HSPA5 (0.51) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL7942322 | 0.84 | GAA (0.51) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL8030261 | 0.83 | GAA (0.62) | CYP2C9CYP2C19HIF1ASMN1; SMN2CYP2D6 | |
| SCHEMBL7941106 | 0.82 | IAPP (0.42) | SMN1; SMN2GAAKMT2AALDH1A1CA2 | |
| SCHEMBL7940420 | 0.81 | GAA (0.53) | CYP2C9CYP2C19HIF1ASMN1; SMN2GAA | |
| SCHEMBL7941083 | 0.80 | GAA (0.53) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL7944770 | 0.78 | HSPA5 (0.47) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL7943132 | 0.78 | GAA (0.51) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL3440651 | 0.77 | HSPA5 (0.62) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075159-A | USE AS A STABILIZER FOR AN ORGANIC MATERIAL SUCH AS THERMOPLASTIC RESINS, THERMOSETTING RESINS, NATURAL OR SYNTHETIC RUBBERS, MINERAL OILS, LUBRICATING OILS, ADHESIVES AND PAINTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-06-13 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |