Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 5/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019189 | 1.00 | IDO1 (0.38) | IDO1MAT2ASPHK1DRD1RAB9A | |
| SCHEMBL8022343 | 0.89 | IDO1 (0.37) | IDO1MAT2ASPHK1DRD1RAB9A | |
| SCHEMBL9008464 | 0.89 | IDO1 (0.37) | IDO1MAT2ASPHK1DRD1RAB9A | |
| SCHEMBL8022344 | 0.89 | IDO1 (0.37) | IDO1MAT2ASPHK1DRD1RAB9A | |
| SCHEMBL8022342 | 0.89 | IDO1 (0.37) | IDO1MAT2ASPHK1DRD1RAB9A | |
| SCHEMBL8018953 | 0.86 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL8018951 | 0.86 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL8582026 | 0.83 | SPHK1 (0.34) | SPHK1RAB9ADRD2CYP2C9HRH3 | |
| SCHEMBL8582029 | 0.83 | SPHK1 (0.34) | SPHK1RAB9ADRD2CYP2C9HRH3 | |
| SCHEMBL8582024 | 0.83 | SPHK1 (0.34) | SPHK1RAB9ADRD2CYP2C9HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670322-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0670322-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |