Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.85 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.85 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.85 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.85 |
| ▸ | TP53 | P04637 | 5/20 | 0.85 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | RET | P07949 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | KDR | P35968 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12941005 | 0.86 | MKNK2 (0.75) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL12941170 | 0.85 | CSNK2A2 (0.75) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL7652737 | 0.83 | MEN1 (0.68) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL25239822 | 0.81 | TP53 (0.67) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL8006203 | 0.81 | MAPT (0.57) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL30667420 | 0.81 | MAPT (0.76) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL8709977 | 0.81 | MAPT (0.71) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL4650064 | 0.80 | MAPT (1.00) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL10037935 | 0.80 | TP53 (1.00) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL4648920 | 0.78 | CSNK2A2 (1.00) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666265-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2000-01-26 | — | — | EP | disclosed |
| US-5527786-A | ANTIDIABETIC AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0666265-A1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-08-09 | — | — | EP | disclosed |