Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ME3 | Q16798 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229190 | 1.00 | EPHX2 (0.49) | EPHX2MAPTKMT2AMEN1HDAC8 | |
| SCHEMBL8019412 | 1.00 | EPHX2 (0.49) | EPHX2MAPTKMT2AMEN1HDAC8 | |
| SCHEMBL8014015 | 1.00 | EPHX2 (0.49) | EPHX2MAPTKMT2AMEN1HDAC8 | |
| SCHEMBL9540597 | 1.00 | EPHX2 (0.49) | EPHX2MAPTKMT2AMEN1HDAC8 | |
| SCHEMBL10885755 | 0.82 | EPHX2 (0.49) | EPHX2MAPTKMT2AMEN1HDAC8 | |
| SCHEMBL10885758 | 0.82 | EPHX2 (0.49) | EPHX2MAPTKMT2AMEN1HDAC8 | |
| SCHEMBL10884929 | 0.82 | EPHX2 (0.49) | EPHX2MAPTKMT2AMEN1HDAC8 | |
| SCHEMBL10884934 | 0.82 | EPHX2 (0.49) | EPHX2MAPTKMT2AMEN1HDAC8 | |
| SCHEMBL10884851 | 0.82 | EPHX2 (0.49) | EPHX2MAPTKMT2AMEN1HDAC8 | |
| SCHEMBL11363289 | 0.81 | EPHX2 (0.46) | EPHX2MAPTKMT2AMEN1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077952-A | Cephaloporins and homologues | PFIZER INC. (US) | 2000-06-20 | — | — | US | disclosed |
| US-6020329-A | Cephaloporins and homologues, preparations and pharmaceutical compositions | PZIFER INC. (US) | 2000-02-01 | — | — | US | disclosed |
| US-6001997-A | Cephalosporins and homologues, preparations and pharmaceutical compositions | BATESON JOHN HARGREAVES (GB) | 1999-12-14 | — | — | US | disclosed |
| US-4342760-A | ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-08-03 | — | — | US | disclosed |
| US-4264597-A | FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD., NO. 3, 4-CHOME, DOSHOMACHI, HIGASHI-KU, OSAKA, JAPAN | 1981-04-28 | — | — | US | disclosed |