Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319939 | 0.82 | SLC6A4 (0.57) | MCHR1HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL7319934 | 0.82 | SLC6A4 (0.57) | MCHR1HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL11389782 | 0.81 | MCHR1 (0.61) | MCHR1MEN1KMT2ACHRM3LMNA | |
| SCHEMBL11389788 | 0.81 | MCHR1 (0.61) | MCHR1MEN1KMT2ACHRM3LMNA | |
| SCHEMBL4486114 | 0.78 | MEN1 (0.60) | MCHR1HTR2AHTR2BSIGMAR1SLC6A4 | |
| SCHEMBL4486120 | 0.78 | MEN1 (0.60) | MCHR1HTR2AHTR2BSIGMAR1SLC6A4 | |
| SCHEMBL7304622 | 0.78 | S1PR1 (0.67) | MCHR1MEN1KMT2ACHRM3LMNA | |
| SCHEMBL7304629 | 0.78 | S1PR1 (0.67) | MCHR1MEN1KMT2ACHRM3LMNA | |
| Hydrochloric Acid SCHEMBL25415886 | 0.78 | HTR2A (0.55) | MCHR1HTR2AHTR2CHTR2BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL25415884 | 0.78 | HTR2A (0.55) | MCHR1HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045693-A1 | AMINOPHENOXYACETIC ACID DERIVATIVES AS NEUROPROTECTANTS | SUNTORY LIMITED (JP) | 2000-10-25 | — | — | EP | disclosed |
| WO-2000023076-A1 | AMINOPHENOXYACETIC ACID DERIVATIVES AS NEUROPROTECTANTS | SUNTORY LIMITED (JP) | 2000-04-27 | — | — | WO | disclosed |