Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 19/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021539 | 0.88 | AVPR1B (0.53) | AVPR1BKDM4EPSMD14ALDH1A1MAPT | |
| SCHEMBL4308546 | 0.87 | AVPR1B (0.62) | AVPR1B | |
| SCHEMBL4304470 | 0.86 | AVPR1B (0.61) | AVPR1B | |
| SCHEMBL4302531 | 0.85 | AVPR1B (0.50) | AVPR1B | |
| SCHEMBL4305682 | 0.85 | AVPR1B (0.48) | AVPR1B | |
| SCHEMBL8010651 | 0.83 | AVPR1B (0.66) | AVPR1B | |
| SCHEMBL4301457 | 0.81 | AVPR1B (0.68) | AVPR1B | |
| SCHEMBL8019480 | 0.81 | AVPR1B (0.56) | AVPR1B | |
| SCHEMBL8024869 | 0.79 | AVPR1B (0.65) | AVPR1B | |
| SCHEMBL4305750 | 0.79 | AVPR1B (0.49) | AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009130231-A1 | PYRROLO [1, 2-A] PYRAZINE DERIVATIVES AS VASOPRESSIN VIB RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | WO | disclosed |