Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019155 | 1.00 | AKR1C4 (0.32) | AKR1C4AKR1C3AKR1C2NLRP3ABL1 | |
| SCHEMBL8019498 | 1.00 | AKR1C4 (0.32) | AKR1C4AKR1C3AKR1C2NLRP3ABL1 | |
| SCHEMBL8023304 | 0.85 | TSHR (0.41) | — | |
| SCHEMBL8021283 | 0.85 | TSHR (0.41) | — | |
| SCHEMBL7720948 | 0.82 | AKR1C4 (0.32) | AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL8008885 | 0.82 | AKR1C4 (0.32) | AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7720944 | 0.82 | AKR1C4 (0.32) | AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL8008883 | 0.82 | AKR1C4 (0.32) | AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7717242 | 0.81 | AKR1C4 (0.39) | AKR1C4AKR1C3AKR1C2NLRP3 | |
| SCHEMBL7717295 | 0.81 | AKR1C4 (0.39) | AKR1C4AKR1C3AKR1C2NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114364-A | 2-((SUBSTITUTED)ALKYL(THIO, SULFONYL, OR SULFOXY)METHYL), 3-(CARBOXYL OR ALIPHATIC HYDROCARBONYL)CYCLOPENTAN-1-ONE DERIVATIVES, EXCEPT CYSTACYCLIN; USE AS NEURON DIFFERENTIATION ACCELERATOR | NIPPON KAYAKU CO., LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0976709-A1 | 2,3-DISUBSTITUTED CYCLOPENTANONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | NIPPON KAYAKU CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |