Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390361 | 0.81 | — | — | |
| SCHEMBL12462742 | 0.80 | NPSR1 (0.38) | NPSR1SMN1; SMN2KCNA3LMNAMEN1 | |
| SCHEMBL3880676 | 0.78 | FFAR3 (0.37) | NPSR1SMN1; SMN2KCNA3LMNAMEN1 | |
| SCHEMBL15867796 | 0.78 | MAPK1 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL2069818 | 0.78 | POLB (0.42) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15967442 | 0.77 | NPSR1 (0.35) | NPSR1SMN1; SMN2KCNA3LMNAMEN1 | |
| SCHEMBL3972954 | 0.77 | NPSR1 (0.35) | NPSR1SMN1; SMN2KCNA3LMNAMEN1 | |
| SCHEMBL15166837 | 0.77 | NPSR1 (0.35) | NPSR1SMN1; SMN2KCNA3LMNAMEN1 | |
| SCHEMBL15166693 | 0.77 | NPSR1 (0.35) | NPSR1SMN1; SMN2KCNA3LMNAMEN1 | |
| SCHEMBL374351 | 0.77 | NPSR1 (0.52) | NPSR1LMNAMEN1KMT2ACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971888-A1 | 2-ALKYL-19-NOR-VITAMIN D COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998041500-A1 | 2-ALKYL-19-NOR-VITAMIN D COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1998-09-24 | — | — | WO | disclosed |