Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.43 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647695 | 0.89 | SRD5A2 (0.46) | GRIN1GRIN2BNR1I3CDK5CDK5R1 | |
| SCHEMBL7609110 | 0.88 | GRIN1 (0.45) | GRIN1GRIN2BNR1I3MBOAT4CDK5 | |
| SCHEMBL9547062 | 0.88 | GRIN1 (0.45) | GRIN1GRIN2BNR1I3MBOAT4CDK5 | |
| SCHEMBL9185884 | 0.87 | CDK5 (0.42) | GRIN1GRIN2BNR1I3MBOAT4CDK5 | |
| SCHEMBL4731758 | 0.85 | SRD5A2 (0.50) | GRIN1GRIN2BNR1I3CDK5CDK5R1 | |
| SCHEMBL8764684 | 0.85 | GRIN1 (0.38) | GRIN1GRIN2BNR1I3 | |
| SCHEMBL10699453 | 0.84 | GRIN1 (0.38) | GRIN1GRIN2BNR1I3MBOAT4CDK5 | |
| SCHEMBL16235951 | 0.82 | NR1I3 (0.41) | GRIN1GRIN2BNR1I3CDK5CDK5R1 | |
| SCHEMBL9110720 | 0.82 | NR1I3 (0.48) | GRIN1GRIN2BNR1I3MBOAT4CDK5 | |
| SCHEMBL15549709 | 0.82 | NR1I3 (0.48) | GRIN1GRIN2BNR1I3MBOAT4CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970105-A1 | PROCESS FOR PREPARING CARBOXAMIDO-4-AZASTEROIDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-12 | — | — | EP | disclosed |
| WO-1999035161-A1 | PROCESS FOR PREPARING CARBOXAMIDO-4-AZASTEROIDS | PHARMACIA & UPJOHN SPA (IT) | 1999-07-15 | — | — | WO | disclosed |