⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820463 | 0.91 | — | — | |
| SCHEMBL8105922 | 0.87 | — | — | |
| SCHEMBL8090642 | 0.86 | — | — | |
| SCHEMBL8098242 | 0.84 | — | — | |
| SCHEMBL8104237 | 0.84 | — | — | |
| SCHEMBL8016554 | 0.81 | — | — | |
| SCHEMBL8099264 | 0.80 | — | — | |
| SCHEMBL7846803 | 0.79 | — | — | |
| SCHEMBL8012904 | 0.79 | — | — | |
| SCHEMBL8090662 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100264-A | 5H, 10H-imidazo [1,2-A] indeno [1,2-E] pyrazin-4-one derivatives, their preparation, their intermediates and medicaments containing them | RHONE-POULENC RORER, S.A. (FR) | 2000-08-08 | — | — | US | disclosed |
| US-5990108-A | USEFUL AS ANTAGONISTS OF THE ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (AMPA) RECEPTOR, ALSO KNOWN AS THE QUISQUALATE RECEPTOR, AND AS ANTAGONISTS OF THE N-METHYL-D-ASPARTATE (NMDA) RECEPTOR | RHONE POULENC RORER S.A. (FR) | 1999-11-23 | — | — | US | disclosed |