Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191023 | 0.88 | AR (0.54) | ARPGR | |
| SCHEMBL8027038 | 0.82 | AR (0.56) | ARIGF1RPGR | |
| SCHEMBL8010572 | 0.82 | AR (0.46) | ARIGF1RPGR | |
| SCHEMBL1974592 | 0.76 | AR (0.65) | AR | |
| SCHEMBL8015151 | 0.76 | AR (0.51) | ARPGR | |
| SCHEMBL3806689 | 0.74 | AR (0.60) | ARPGR | |
| SCHEMBL3991583 | 0.74 | AR (0.58) | ARIGF1R | |
| SCHEMBL1208028 | 0.73 | AR (0.63) | ARPGR | |
| SCHEMBL3532540 | 0.73 | AR (0.51) | ARIGF1RPGR | |
| SCHEMBL14295099 | 0.73 | AR (0.42) | ARIGF1RPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097998-A1 | ARYLCHALCOGENO-ARYLALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |