⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813216 | 0.95 | — | — | |
| SCHEMBL523017 | 0.84 | — | — | |
| SCHEMBL4524059 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL4517659 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL4536407 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL4536124 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL4539634 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL4526516 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL4528581 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL4528436 | 0.82 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | disclosed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | disclosed |
| EP-0653432-A1 | Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | disclosed |