Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349878 | 1.00 | SRD5A1 (0.72) | SRD5A1SRD5A2 | |
| SCHEMBL4187755 | 1.00 | SRD5A1 (0.72) | SRD5A1SRD5A2 | |
| SCHEMBL4187752 | 1.00 | SRD5A1 (0.72) | SRD5A1SRD5A2 | |
| SCHEMBL13604091 | 1.00 | SRD5A1 (0.72) | SRD5A1SRD5A2 | |
| SCHEMBL8724807 | 0.92 | SRD5A1 (0.71) | SRD5A1SRD5A2 | |
| SCHEMBL9571051 | 0.90 | SRD5A1 (0.72) | SRD5A1SRD5A2 | |
| SCHEMBL13604098 | 0.90 | SRD5A1 (0.72) | SRD5A1SRD5A2 | |
| SCHEMBL2376048 | 0.90 | SRD5A1 (0.72) | SRD5A1SRD5A2 | |
| SCHEMBL11424034 | 0.89 | SRD5A1 (0.71) | SRD5A1SRD5A2 | |
| SCHEMBL11424038 | 0.89 | SRD5A1 (0.71) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664812-B1 | 17-BETA-ARYL ESTER CARBOXYLATES OF 4-AZA-5-ALPHA-ANDROSTANE-3-ONES | MERCK & CO INC (US) | 2000-01-05 | — | — | EP | disclosed |
| EP-0664812-A4 | 17 -g(b)-ARYL ESTER CARBOXYLATES OF 4-AZA-5-g(a)-ANDROSTANE-3-ONES. | MERCK & CO INC (US) | 1995-10-25 | — | — | EP | disclosed |
| EP-0664812-A1 | 17 $g(b)-ARYL ESTER CARBOXYLATES OF 4-AZA-5$g(a)-ANDROSTANE-3-ONES | MERCK & CO. INC. (US) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994007860-A1 | 17 β-ARYL ESTER CARBOXYLATES OF 4-AZA-5α-ANDROSTANE-3-ONES | MERCK & CO., INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| US-5278159-A | Steroid enzyme inhibitor | MERCK & CO., INC. (US) | 1994-01-11 | — | — | US | disclosed |
| US-4220775-A | Preparation of 4-aza-17-substituted-5α-androstan-3-ones useful as 5α-reductase inhibitors | MERCK & CO., INC. (US) | 1980-09-02 | — | — | US | disclosed |