SCHEMBL8021152

SCHEMBL8021152

CCC(=O)Nc1cccc2ccc(O)cc12

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 17/20 0.61
KDM4E B2RXH2 1/20 0.58
MEN1 O00255 1/20 0.58
MAPT P10636 1/20 0.58
RAB9A P51151 1/20 0.58
KMT2A Q03164 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11722439 0.90 TRPV1 (0.67) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL11876012 0.88 RXFP1 (0.53) TRPV1MEN1MAPTKMT2A
SCHEMBL6822698 0.85 TRPV1 (0.61) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL6416667 0.85 TRPV1 (0.64) TRPV1KDM4EMEN1MAPTRAB9A
Hydrochloric Acid SCHEMBL10899498 0.84 TRPV1 (0.57) TRPV1KDM4EMEN1MAPTRAB9A
Hydrochloric Acid SCHEMBL7637050 0.84 TRPV1 (0.60) TRPV1KDM4EMEN1MAPTRAB9A
Hydrochloric Acid SCHEMBL10893600 0.83 TRPV1 (0.59) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL30125341 0.83 TRPV1 (0.64) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL1413170 0.83 TRPV1 (0.64) TRPV1KDM4EMEN1MAPTRAB9A
Iodide SCHEMBL10893659 0.83 TRPV1 (0.56) TRPV1KDM4EMEN1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016111957-A1 CHLOROQUINOLINE TRIAZOLE COMPOUNDS, COMPOSITION AND USES ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) 2016-07-14 WO disclosed
EP-0648816-B1 Dyeing of leather with dyestuff mixtures CIBA SC HOLDING AG (CH) 2000-01-26 EP disclosed
EP-0648816-A1 Dyeing of leather with dyestuff mixtures CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0307357-B1 Process for the preparation of azo dyes capable of being metallized CIBA GEIGY AG (CH) 1994-06-22 EP disclosed
EP-0385939-B1 Process for the preparation of metallisable azodyes CIBA GEIGY AG (CH) 1994-06-01 EP disclosed
EP-0061670-B2 Process for dyeing leather and pelts with dye mixtures CIBA GEIGY AG (CH) 1994-06-01 EP disclosed
US-5204453-A Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
EP-0320446-B1 PROCESS FOR THE PREPARATION OF METALLIZABLE AZO DYES CIBA-GEIGY AG (CH) 1993-04-07 EP disclosed
US-5196518-A Dizonium slat coupled with hydroxy compound CIBA-GEIGY CORPORATION (US) 1993-03-23 US disclosed
US-5126435-A Reacting azo compound and coupling agent in presence of zinc salt and inert gas; high speed, efficiency, simplification CIBA-GEIGY CORPORATION (US) 1992-06-30 US disclosed
EP-0019851-A1 1:2 Chromium complex dyestuffs of the azomethine and/or azo series, their preparation and use in dyeing and printing polyamide or cellulose materials CIBA-GEIGY AG (CH) 1980-12-10 EP disclosed
US-4215042-A PRINTING AND DYEING OF POLYAMIDES; COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1980-07-29 US disclosed
EP-0009466-A1 1 : 2-Bis-chromium-complex dyestuffs from polyazo- or disazo-azomethine compounds, their preparation and their use CIBA-GEIGY AG (CH) 1980-04-02 EP disclosed
EP-0005207-A2 Bis-1:2 chrome-disazo-bisazo methine dyestuffs, their preparation and use for dyeing of leather CIBA-GEIGY AG (CH) 1979-11-14 EP disclosed
US-4116952-A POLYAMIDES CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4033942-A Chromium complex dye, including azo and azo methine dye compounds CIBA-GEIGY AG (CH) 1977-07-05 US disclosed
US-3978037-A POLYAMIDES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed