SCHEMBL8021435

SCHEMBL8021435

B.CC(C)CN(CC(C)C)CC(C)C

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
MAPK1 P28482 1/20 0.50
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41
PIK3CD O00329 1/20 0.33
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65000 0.96 CYP1A2 (0.53) CYP1A2MAPK1CA12CA1CA2
Fluoride SCHEMBL1056432 0.92 CYP1A2 (0.50) CYP1A2MAPK1CA12CA1CA2
Hydrochloric Acid SCHEMBL2139422 0.92 CYP1A2 (0.50) CYP1A2MAPK1CA12CA1CA2
Ammonia Solution, Strong SCHEMBL5964780 0.92 CYP1A2 (0.50) CYP1A2MAPK1CA12CA1CA2
Methylamine SCHEMBL6867533 0.88 MAPK1 (0.48) CYP1A2MAPK1CA12CA1CA2
SCHEMBL9720290 0.80 CYP1A2 (0.48) CYP1A2MAPK1CA12CA1CA2
SCHEMBL15016045 0.80 CYP1A2 (0.48) CYP1A2MAPK1CA12CA1CA2
SCHEMBL5669823 0.79 MAPK1 (0.42) CYP1A2MAPK1CA12CA1CA2
SCHEMBL7776722 0.79 CYP1A2 (0.42) CYP1A2MAPK1CA12CA1CA2
SCHEMBL7054650 0.79 CYP1A2 (0.42) CYP1A2MAPK1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0682031-B1 Silacyclohexane-based carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound SHINETSU CHEMICAL CO (JP) 2000-03-22 EP disclosed
US-5527490-A Silacyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-18 US disclosed
EP-0682031-A1 Silacyclohexane carbaldehyde compounds and processes for preparing silycyclohexane-based liquid crystal compounds from the carbaldehyde compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-11-15 EP disclosed
US-4855440-A COLORFASTNESS SHEREX CHEMICAL COMPANY, INC. (US) 1989-08-08 US disclosed