SCHEMBL8021782

SCHEMBL8021782

CCCCCCc1c(O)ccc(C(=O)O)c1CC

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 4/20 0.57
PPARA Q07869 3/20 0.57
RARB P10826 3/20 0.49
PPARG P37231 2/20 0.47
BID P55957 3/20 0.47
MCL1 Q07820 3/20 0.47
BCL2L1 Q07817 2/20 0.47
BAK1 Q16611 2/20 0.47
EP300 Q09472 1/20 0.47
KAT2A Q92830 1/20 0.47
KAT2B Q92831 1/20 0.47
KAT5 Q92993 1/20 0.47
SAE1 Q9UBE0 1/20 0.47
RARA P10276 1/20 0.46
RARG P13631 1/20 0.46
PLK1 P53350 1/20 0.44
TYR P14679 1/20 0.44
STAT3 P40763 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL987553 0.94 KAT8 (0.57) KAT8PPARARARBPPARGBID
SCHEMBL5180302 0.94 KAT8 (0.57) KAT8PPARARARBPPARGBID
SCHEMBL987957 0.94 KAT8 (0.60) KAT8PPARARARBPPARGBID
SCHEMBL5317590 0.94 KAT8 (0.60) KAT8PPARARARBPPARGBID
SCHEMBL5179734 0.94 KAT8 (0.60) KAT8PPARARARBPPARGBID
SCHEMBL8364756 0.90 PPARA (0.55) KAT8PPARARARBPPARGBID
SCHEMBL28624935 0.87 KAT8 (0.49) KAT8PPARARARBPPARGBID
SCHEMBL29104710 0.87 KAT8 (0.51) KAT8PPARARARBPPARGBID
SCHEMBL31351897 0.87 KAT8 (0.51) KAT8PPARARARBPPARGBID
SCHEMBL8772723 0.87 MCL1 (0.47) KAT8PPARAMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585787-B1 Silver halide photographic material containing selenium compound FUJI PHOTO FILM CO LTD (JP) 2000-02-16 EP disclosed
US-5550015-A PRECIPITATING A SILVERBROMOIODIDE CORE BY DOUBLE JET METHOD; RIPENING; GROWING GRAINS BY ADDING SILVER IONS FROM ONE SOLUTION AND BROMIDE AND IODIDE IONS FROM ANOTHER AGFA-GEVAERT AG (DE) 1996-08-27 US disclosed
US-5462843-A Silver halide emulsion doped with at least one metal compound AGFA-GEVAERT AG (DE) 1995-10-31 US disclosed
US-5445928-A Improved reproduction at high density with excellent color separation; using gap sensitizer in coupler-free layer containing silver halide emulsion AGFA-GEVAERT AG (DE) 1995-08-29 US disclosed
US-5407789-A Sharpness, graininess AGFA-GEVAERT AG (DE) 1995-04-18 US disclosed
US-5385813-A A green-photosensitive silver halide emulsion containing a magenta coupler a phenyl amidosulfonyl benzothiazoles; adjust to any desired sensitivity AGFA-GEVAERT AG (DE) 1995-01-31 US disclosed
US-5360704-A Color photographic recording material AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1994-11-01 US disclosed
US-5354649-A Silver halide emulsion of silver chloride and silver iodide and a coupler AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed
US-5306605-A Improved sharpness AGFA-GEVAERT AG 1994-04-26 US disclosed
EP-0585787-A2 Silver halide photographic material containing selenium compound FUJI PHOTO FILM CO., LTD. (JP) 1994-03-09 EP disclosed
US-5200301-A COLOR PHOTOGRAPHIC RECORDING MATERIAL AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1993-04-06 US disclosed
US-5143823-A N-Acylsulfamoyl-Substituted A-Acylacetanilide Yellow Coupler AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1992-09-01 US disclosed
US-5134059-A Magenta pyrazolone couplers BAYER AKTIENGESELLSCHAFT (DE) 1992-07-28 US disclosed
US-5134061-A Nondiffusing \"building blocks\" (couplers, development inhibitors etc.) having a sulfonamide group and a secondary branched alkyl of 14 carbons or more; low-melting; crystal growth inhibitors; high-density color AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1992-07-28 US disclosed
US-5089381-A SILVER HALIDE RECORDING MATERIAL AGFA-GEVAERT AG (DE) 1992-02-18 US disclosed
US-5006457-A Triazole derivatives as antifogging agents BAYER AKTIENGESELLSCHAFT (DE) 1991-04-09 US disclosed
US-4992362-A Precipitation of silver halide in presence of gelatin; uniform grain distribution AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1991-02-12 US disclosed
US-4978607-A CONTAINING GELATIN, MODIFIED WITH MONOFUNCTIONAL ACID DERIVATIVE, AND HARDENER, A CARBAMOYL PYRIDINIUM SALT; WITHOUT RETICULATED GRAIN AGFA-GEVAERT AKTIENGESSELLSCHAFT (DE) 1990-12-18 US disclosed
US-4401520-A Process for the preparation of screen printing stencils by an electroplating method HOECHST AKTIENGESELLSCHAFT (DE) 1983-08-30 US disclosed
US-4379834-A Process for cleaning copper-containing metal surfaces HOECHST AKTIENGESELLSCHAFT (DE) 1983-04-12 US disclosed