SCHEMBL8021994

SCHEMBL8021994

CCCCCCCCOc1cccc2c3c(ccc12)C=CC(C)(C)O3

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HTT P42858 1/20 0.40
HTR1B P28222 2/20 0.39
CYP2C9 P11712 2/20 0.38
HTR1D P28221 1/20 0.38
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
MCHR1 Q99705 2/20 0.36
NR1I2 O75469 1/20 0.35
LMNA P02545 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
ADRA2A P08913 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
HTR2B P41595 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31290574 1.00 CNR1 (0.40) CNR1CNR2MEN1KMT2AHTT
SCHEMBL8899536 0.88 MEN1 (0.32) CNR1CNR2MEN1KMT2AHTT
SCHEMBL8131792 0.87 MEN1 (0.40) CNR1CNR2MEN1KMT2AHTT
SCHEMBL8136944 0.79 CA12 (0.43)
SCHEMBL8899532 0.79 PPARD (0.30)
SCHEMBL6938193 0.76 CNR1 (0.57) CNR1CNR2MEN1KMT2AHTT
SCHEMBL2917038 0.76 CNR1 (0.57) CNR1CNR2MEN1KMT2AHTT
SCHEMBL347409 0.76 CNR1 (0.57) CNR1CNR2MEN1KMT2AHTT
SCHEMBL19612278 0.70 CNR1 (0.47) CNR1CNR2MEN1KMT2AHTT
SCHEMBL23271677 0.69 CNR1 (0.61) CNR1CNR2MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438147-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL OBTAINED FROM COMPOSITION, AND PLASTIC LENS MITSUI CHEMICALS INC (JP) 2023-06-21 EP disclosed
CN-110914322-B Polymerizable composition for optical material, and use thereof 三井化学株式会社 2022-08-23 CN disclosed
CN-110831992-B Polymerizable composition for optical material and molded article 三井化学株式会社 2022-08-23 CN disclosed
US-11414515-B2 Polymerizable composition for optical material and optical material and plastic lens obtainable from same composition MITSUI CHEMICALS, INC. (JP) 2022-08-16 US disclosed
CN-108884209-B Polymerizable composition for optical material, optical material obtained from the composition, and plastic lens 三井化学株式会社 2021-05-25 CN disclosed
CN-107209284-B Polymerizable composition for optical material, optical material obtained from the composition, and plastic lens 三井化学株式会社 2020-11-13 CN disclosed
US-20200207947-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND APPLICATION THEREOF MITSUI CHEMICALS, INC. (JP) 2020-07-02 US disclosed
EP-3351573-B1 MOLDED BODY AND POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS MITSUI CHEMICALS INC (JP) 2020-06-17 EP disclosed
US-20200148856-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND MOLDED PRODUCT MITSUI CHEMICALS, INC. (JP) 2020-05-14 US disclosed
EP-3650480-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND MOLDED BODY Mitsui Chemicals, Inc. (JP) 2020-05-13 EP disclosed
EP-0773272-A1 PHOTOCHROMIC CURABLE COMPOSITION TOKUYAMA CORPORATION (JP) 1997-05-14 EP disclosed
EP-0773273-A1 PROCESS FOR THE PRODUCTION OF PHOTOCHROMIC PRODUCT OF CURING TOKUYAMA CORPORATION (JP) 1997-05-14 EP disclosed
US-5621017-A PHOTOCHROMIC COMPOSITION INCLUDING RADICAL POLYMERIZABLE MONOMER, CHROMENE AND/OR SPIROOXAZINE BASED PHOTOCHROMIC COMPOUND, PHOTOPOLYMERIZATION INITIATOR TOKUYAMA CORPORATION (JP) 1997-04-15 US disclosed
EP-0696582-A1 Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides TOKUYAMA CORPORATION (JP) 1996-02-14 EP disclosed
EP-0681018-A2 Photochromic composition and method of producing photochromic cured product TOKUYAMA CORPORATION (JP) 1995-11-08 EP disclosed
US-5462698-A Lenses TOKUYAMA CORPORATION (JP) 1995-10-31 US disclosed
US-5395566-A Addition polymerizable composition, epoxy monomer, imide or anhydride containing fused ring photochromic compound, lenses TOKUYAMA CORPORATION (JP) 1995-03-07 US disclosed
EP-0629626-A2 Cyclopropyl-substituted spiro-photochromic compounds TOKUYAMA CORPORATION (JP) 1994-12-21 EP disclosed
EP-0619358-A1 Photochromic composition TOKUYAMA CORPORATION (JP) 1994-10-12 EP disclosed
EP-0559439-A2 Photochromic composition TOKUYAMA CORPORATION (JP) 1993-09-08 EP disclosed