Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020384 | 0.98 | METAP1 (0.44) | METAP1CYP1A2METAP2SIGMAR1HPGD | |
| SCHEMBL8020307 | 0.93 | — | — | |
| SCHEMBL1678614 | 0.87 | — | — | |
| SCHEMBL1524668 | 0.80 | CYP1A2 (0.48) | METAP1CYP1A2METAP2SIGMAR1BCHE | |
| SCHEMBL436792 | 0.80 | CYP1A2 (0.48) | METAP1CYP1A2METAP2SIGMAR1BCHE | |
| SCHEMBL9384040 | 0.80 | CYP1A2 (0.48) | METAP1CYP1A2METAP2SIGMAR1BCHE | |
| SCHEMBL1338880 | 0.77 | CYP1A2 (0.44) | METAP1CYP1A2METAP2SIGMAR1 | |
| SCHEMBL24794912 | 0.76 | CYP1A2 (0.44) | METAP1CYP1A2METAP2SIGMAR1 | |
| SCHEMBL22229853 | 0.76 | METAP1 (0.52) | METAP1CYP1A2METAP2SIGMAR1HPGD | |
| SCHEMBL8282831 | 0.76 | CYP1A2 (0.44) | METAP1CYP1A2METAP2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971904-A1 | NOVEL 1-AMINO-3 BENZYL URACILS | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042682-A1 | NOVEL 1-AMINO-3 BENZYL URACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-01 | — | — | WO | disclosed |