Benzene

Benzene

SCHEMBL8022649

c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 1.00
TP53 P04637 1/20 1.00
ALDH1A1 P00352 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL8023353 1.00 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
Benzene SCHEMBL8107103 1.00 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
Benzene SCHEMBL8430159 1.00 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
Benzene SCHEMBL1330958 1.00
Benzene SCHEMBL8021516 1.00 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
SCHEMBL1112772 1.00 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
Benzene SCHEMBL8576855 1.00 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
Benzene SCHEMBL10780001 1.00 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
SCHEMBL1086976 1.00 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
Benzene SCHEMBL194 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6054419-A Mixture of alkyl-aryl-sulfonates of alkaline earth metals, its application as an additive for lubricating oil, and methods of preparation CHEVRON CHEMICAL COMPANY LLC (US) 2000-04-25 US disclosed
US-5430086-A Rubber composition for tire treads SUMITOMO RUBBER INDUSTRIES (JP) 1995-07-04 US disclosed
US-4645713-A HEAT GRAPHITIZATION OF A CARBON FILM FORMED BY PLASMA-DISCHARGED-TREATED HYDROCARBON GAS AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1987-02-24 US disclosed
US-4184988-A Process for the sulfonation of an elastomeric polymer EXXON RESEARCH & ENGINEERING CO. (US) 1980-01-22 US disclosed