Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.95 |
| ▸ | MAOA | P21397 | 1/20 | 0.91 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.77 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010516 | 1.00 | CHRM2 (0.95) | CHRM2MAOAMEN1KMT2ATDP1 | |
| SCHEMBL8010497 | 1.00 | CHRM2 (0.95) | CHRM2MAOAMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL8021494 | 0.98 | CHRM2 (0.91) | CHRM2MAOAMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL8020830 | 0.98 | CHRM2 (0.91) | CHRM2MAOAMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL8025354 | 0.98 | CHRM2 (0.91) | CHRM2MAOAMEN1KMT2ATDP1 | |
| SCHEMBL8021930 | 0.98 | CHRM2 (1.00) | CHRM2MAOAMEN1KMT2ATDP1 | |
| SCHEMBL3041221 | 0.98 | CHRM2 (1.00) | CHRM2MAOAMEN1KMT2ATDP1 | |
| SCHEMBL8021157 | 0.98 | CHRM2 (1.00) | CHRM2MAOAMEN1KMT2ATDP1 | |
| SCHEMBL8025398 | 0.95 | CHRM2 (0.95) | CHRM2MAOAMEN1KMT2ATDP1 | |
| SCHEMBL7015048 | 0.95 | CHRM2 (0.95) | CHRM2MAOAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114394-A | Polyamine derivatives as radioprotective agents | MERRELL PHARMACEUTICALS INC. (US) | 2000-09-05 | — | — | US | disclosed |