Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.41 |
| ▸ | MC5R | P33032 | 3/20 | 0.39 |
| ▸ | MC3R | P41968 | 3/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MC1R | Q01726 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039020 | 0.92 | SLC2A1 (0.46) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL12990184 | 0.89 | MC4R (0.43) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL11929574 | 0.81 | MC4R (0.47) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL11929564 | 0.81 | MC4R (0.50) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL13034253 | 0.81 | SLC2A1 (0.49) | MC4RMC5RMC3RSLC2A1 | |
| SCHEMBL11929587 | 0.80 | MC4R (0.43) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL11929590 | 0.80 | MC4R (0.42) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL11929586 | 0.79 | MC4R (0.52) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL4669868 | 0.79 | MC4R (0.45) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL11929584 | 0.79 | MC4R (0.45) | MC4RMC5RMC3RSLC2A1MC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080291-A1 | SUBSTITUTED IMIDAZOPYRIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR ANTAGONISTS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2009-07-02 | — | — | WO | disclosed |