Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020365 | 0.84 | PPARG (0.39) | PPARGPPARAMAPTHTTKDM4E | |
| SCHEMBL8020369 | 0.84 | PPARG (0.39) | PPARGPPARAMAPTHTTKDM4E | |
| SCHEMBL30168591 | 0.83 | PPARG (0.45) | PPARGPPARAL3MBTL1PPARDHPGD | |
| SCHEMBL8024497 | 0.83 | PPARG (0.45) | PPARGPPARAL3MBTL1PPARDHPGD | |
| SCHEMBL8024495 | 0.83 | PPARG (0.45) | PPARGPPARAL3MBTL1PPARDHPGD | |
| SCHEMBL30168595 | 0.82 | PPARG (0.42) | PPARGPPARAMAPTHTTKDM4E | |
| SCHEMBL8026099 | 0.81 | NOTUM (0.37) | PPARGPPARAMAPTKDM4EALDH1A1 | |
| SCHEMBL21675874 | 0.81 | NOTUM (0.37) | PPARGPPARAMAPTKDM4EALDH1A1 | |
| SCHEMBL21647869 | 0.81 | NOTUM (0.37) | PPARGPPARAMAPTKDM4EALDH1A1 | |
| SCHEMBL8026096 | 0.81 | NOTUM (0.37) | PPARGPPARAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975587-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998043949-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-08 | — | — | WO | disclosed |