Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | IGF1R | P08069 | 6/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015270 | 0.88 | AR (0.47) | ARIGF1RPPARGPPARDPPARA | |
| SCHEMBL2217656 | 0.81 | IGF1R (0.48) | ARIGF1RPPARGPPARDPPARA | |
| SCHEMBL2218688 | 0.74 | PPARG (0.52) | ARIGF1RPPARGPPARDPPARA | |
| SCHEMBL8020449 | 0.72 | AR (0.41) | ARIGF1RPPARGPPARDPPARA | |
| SCHEMBL2940644 | 0.72 | IGF1R (0.60) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2217728 | 0.72 | AR (0.52) | ARIGF1RPPARGPPARDPPARA | |
| SCHEMBL2219860 | 0.71 | IGF1R (0.46) | ARIGF1RPPARGPPARDPPARA | |
| SCHEMBL2219331 | 0.70 | IGF1R (0.50) | ARIGF1R | |
| SCHEMBL12438814 | 0.69 | IGF1R (0.49) | ARIGF1R | |
| SCHEMBL2217783 | 0.68 | AR (0.52) | ARIGF1RPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097995-A1 | NOVEL PHENYL-SUBSTITUTED IMIDAZOLIDINES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |