SCHEMBL8024102

SCHEMBL8024102

O=S(=O)(O)Oc1cc(O)c2c(OS(=O)(=O)O)cccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP1 P07148 1/20 0.47
CISD1 Q9NZ45 1/20 0.45
TYR P14679 1/20 0.44
TSHR P16473 1/20 0.38
DUSP5 Q16690 1/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
STS P08842 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
F10 P00742 2/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
DNMT1 P26358 1/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
KMT2A Q03164 1/20 0.34
MCL1 Q07820 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10773617 0.80 TSHR (0.44) FABP1CISD1TYRTSHRDUSP5
SCHEMBL10872659 0.79 CISD1 (0.51) CISD1TYRCA1CA2CA9
SCHEMBL6747882 0.77 FABP1 (0.63) FABP1TSHRGLAGAAMEN1
SCHEMBL10771564 0.76 CISD1 (0.39) FABP1CISD1TYRTSHRDUSP5
SCHEMBL9800216 0.76 CISD1 (0.39) FABP1CISD1TYRTSHRDUSP5
SCHEMBL8766960 0.76 NQO2 (0.53) CISD1TYRCA1CA2CA9
Ammonia Solution, Strong SCHEMBL27454136 0.74 NQO2 (0.52) CISD1TYRCA1CA2CA9
SCHEMBL8770833 0.73 CA1 (0.43) FABP1CISD1TYRCA1CA2
SCHEMBL7625960 0.72 NT5E (0.53) CISD1TYRCA1CA2CA9
SCHEMBL9224372 0.72 CISD1 (0.47) CISD1TYRDUSP5STSGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648816-B1 Dyeing of leather with dyestuff mixtures CIBA SC HOLDING AG (CH) 2000-01-26 EP disclosed
EP-0648816-A1 Dyeing of leather with dyestuff mixtures CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0231147-B1 PROCESS FOR THE TRICHROMATIC DYEING OF LEATHER CIBA-GEIGY AG (CH) 1992-01-15 EP disclosed
EP-0181836-B1 PROCESS FOR IMPROVING THE LIGHT FASTNESS OF DYED LEATHERS CIBA-GEIGY AG (CH) 1988-12-21 EP disclosed
EP-0231147-A2 Process for the trichromatic dyeing of leather CIBA-GEIGY AG (CH) 1987-08-05 EP disclosed
EP-0181836-A1 Process for improving the light fastness of dyed leathers CIBA-GEIGY AG (CH) 1986-05-21 EP disclosed
EP-0061670-B1 PROCESS FOR DYEING LEATHER AND PELTS WITH DYE MIXTURES CIBA-GEIGY AG (CH) 1985-06-12 EP disclosed
EP-0061670-A1 Process for dyeing leather and pelts with dye mixtures CIBA-GEIGY AG (CH) 1982-10-06 EP disclosed