Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024709 | 0.82 | BCL9 (0.64) | BCL9CTNNB1GAAMGLLKMT2A | |
| SCHEMBL7063519 | 0.78 | GAA (0.65) | BCL9CTNNB1GAAMGLLKMT2A | |
| SCHEMBL2294100 | 0.77 | BCL9 (0.76) | BCL9CTNNB1GAAMGLLKMT2A | |
| SCHEMBL7061678 | 0.77 | GAA (0.60) | BCL9CTNNB1GAAMGLLKMT2A | |
| SCHEMBL161868 | 0.76 | BCL9 (0.74) | BCL9CTNNB1GAAMGLLKMT2A | |
| SCHEMBL27716579 | 0.75 | BCL9 (0.73) | BCL9CTNNB1GAAMGLLKMT2A | |
| SCHEMBL3989423 | 0.75 | GAA (0.62) | BCL9CTNNB1GAAMGLLKMT2A | |
| SCHEMBL11583339 | 0.73 | BCL9 (0.61) | BCL9CTNNB1GAAMGLLKMT2A | |
| Alcohol SCHEMBL20595561 | 0.73 | BCL9 (0.66) | BCL9CTNNB1GAAMGLLKMT2A | |
| SCHEMBL28018668 | 0.73 | BCL9 (0.57) | BCL9CTNNB1GAAMGLLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |